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Publications

Insights into cargo sorting by SNX32 and its role in neurite outgrowth. Jini Sugatha, Amulya Priya, Prateek Raj, Ebsy Jaimon, Uma Swaminathan, Anju Jose, Thomas John Pucadyil, Sunando Datta. eLife, 2023
Membrane trafficking. Amulya Priya and Sunando Datta. In Jingshi Shen (eds) Membrane Trafficking. Methods in Molecular Biology, 2022, Volume 2473.
Membrane trafficking. Priyanka Sharma, Sameena Parveen and Sunando Datta. In Jingshi Shen (eds) Membrane Trafficking. Methods in Molecular Biology, 2022, Volume 2473
Syntaxin7 contributes to breast cancer cell invasion by promoting invadopodia formation. Sameena Parveen, Amrita Khamari, Jyothikamala R, Marc G Coppolino and Sunando Datta. J Cell Science (2022)
PI Kinase-EhGEF2-EhRho5 axis contributes to LPA stimulated macropinocytosis in Entamoeba histolytica. Apte A, Manich M, Labruyère E, Datta S. PLoS Pathog. 2022
EhRho6-mediated actin degradation in Entamoeba histolytica is associated with compromised pathogenicity. Narooka AR, Apte A, Yadav P, Murillo JR, Goto-Silva L, Junqueira M, Datta S. Mol Microbiol. 2022

PLP2 drives collective cell migration via ZO-1-mediated cytoskeletal remodeling at the leading edge in human colorectal cancer cells. Dipanjana Ghosh, Ankita Dutta, Anjali Kashyap, Neeraj Upmanyu, Sunando Datta, J Cell Science (2021)
Molecular Insights into E. histolytica Mediated Host Tissue Invasion. Jain M., Tripathi A., Emmanuel M., Verma K., Datta S. In: Guillen N. (eds) Eukaryome Impact on Human Intestine Homeostasis and Mucosal Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-44826-4_19, (2020)
EhC2B, a C2 domain-containing protein, promotes erythrophagocytosis in Entamoeba histolytica via actin nucleation. Aashutosh Tripathi, Megha Jain, Mintu Chandra, Sameena Parveen, Rupali Yadav, Brett M. Collins, Sankar Maiti, Sunando Datta, PLoS Pathog. 2020
SNX27-retromer Assembly Recycles MT1-MMP to Invadopodia and Promotes Breast Cancer Metastasis. Priyanka Sharma , Sameena Parveen , Lekha V Shah , Madhumita Mukherjee , Yannis Kalaidzidis , Anthony J Kozielski , Roberto Rosato, Jenny C Chang , Sunando Datta. J Cell Biol 2020
Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B. Ebsy Jaimon, Aashutosh Tripathi, Arohi Khurana, Dipanjana Ghosh, Jini Sugatha, Sunando Datta, J Biol. Chemistry, 2021

Rab GTPases take centre stage in understanding Entamoeba histolytica biology. Kuldeep Verma, Vijay Kumar Srivastava & Sunando Datta, Small GTPases 2018.
Atypical Switch-I Arginine plays a catalytic role in GTP hydrolysis by Rab21 from Entamoeba histolytica. Kotyada C, et al, Datta S. Biochem Biophys Res Commun 2018
Heavy subunit of cell surface Gal/GalNAc lectin (Hgl) undergoes degradation via endo-lysosomal compartments in Entamoeba histolytica.Verma K, Datta S. Small GTPases 2017
Essential and selective role of SNX12 in transport of endocytic and retrograde cargo.Priya A, Sugatha J, Parveen S, Lacas-Gervais S, Raj P, Gilleron J, Datta S. Journal of Cell Science 2017
Structural and thermodynamic characterization of metal binding in Vps29 from Entamoeba histolytica: Implication in retromer function.Srivastava VK, Yadav R, Natsuki W, Tomar P, Mukherjee M, Gourinath S, Nakada-Tsukui K, Nozaki T, Datta S. Molecular Microbiology. 2017
The monomeric GTPase Rab35 regulates phagocytic cup formation and phagosomal maturation in Entamoeba histolytica. Verma K, Datta S. Journal of Biological Chemistry. 2017 Jan

Role of EhRab7A in phagocytosis of type 1 fimbriated E. coli by Entamoeba histolytica. Verma K, Nozaki T, Datta S. Mol Microbiol. 2016 Oct
Crystal Structure Analysis of Wild Type and Fast Hydrolyzing Mutant of EhRabX3, a Tandem Ras Superfamily GTPase from Entamoeba histolytica. Srivastava VK, Chandra M, Nakano YS, Nozaki T, Datta S. J Mol Biol. 2016 Jan
Deciphering the role of Atg5 in nucleotide dependent interaction of Rab33B with the dimeric complex, Atg5-Atg16L1. Chandra M, Saran R, Datta S. Biochem Biophys Res Commun. 2016 Apr
Role of cysteine residues in the redox-regulated oligomerization and nucleotide binding to EhRabX3. Chandra M, Datta S. Mol Biochem Parasitol. 2016 Aug
Biophysical studies on calcium and carbohydrate binding to carbohydrate recognition domain of Gal/GalNAc lectin from Entamoeba histolytica: insights into host cell adhesion. Yadav R, Verma K, Chandra M, Mukherjee M, Datta S. J Biochem. 2016 Sep
Insights into endosomal maturation of human holo-transferrin in the enteric parasite Entamoeba histolytica: essential roles of Rab7A and Rab5 in biogenesis of giant early endocytic vacuoles. Verma K, Nakano YS, Nozaki T, Datta S. Cell Microbiol. 2015 Dec
Molecular insights into Rab7-mediated endosomal recruitment of core retromer: deciphering the role of Vps26 and Vps35. Priya A, Kalaidzidis I, Kalaidzidis Y, Lambright D, Datta S. Traffic. 2015 Jan

Crystallization and preliminary X-ray analysis of RabX3, a tandem GTPase from Entamoeba histolytica. Srivastava V, Chandra M, Datta S. Acta Crystallogr F Struct Biol Commun. 2014 Jul
Insights into the GTP/GDP cycle of RabX3, a novel GTPase from Entamoeba histolytica with tandem G-domains. Chandra M, Mukherjee M, Srivastava V, Nakano YS, Nozaki T, Datta S. Biochemistry, 2014
New players in the same old game: a system level in silico study to predict type III secretion system and effector proteins in bacterial genomes reveals common themes in T3SS mediated pathogenesis. Sadarangani V, Datta S and Arunachalam M. BMC Research Notes, 2013

Identification of the switch in early-to-late endosome transition.Poteryaev D, Datta S, Ackema K, Zerial M and Spang A. Cell, 2010 Apr 30;141(3):497-508..(Co- First Author).
GTP-binding-defective forms of tissue transglutaminase trigger cell death. Datta S, Antonyak MA, Cerione RA. Biochemistry. 2007 Dec 25;46(51):14819-29. Epub 2007 Dec 1.
Snapshots of RecA protein involving movement of the C-domain and different conformations of the DNA-binding loops: crystallographic and comparative analysis of 11 structures of Mycobacterium smegmatis RecA. Krishna R, Prabu JR, Manjunath GP, Datta S, Chandra NR, Muniyappa K, Vijayan M. J Mol Biol. 2007 Apr 6;367(4):1130-44.
Importance of Ca(2+)-dependent transamidation activity in the protection afforded by tissue transglutaminase against doxorubicin-induced apoptosis. Datta S, Antonyak MA, Cerione RA. Biochemistry. 2006 Nov 7;45(44):13163-74.

Homologous recombination in mycobacteria. K Muniyappa, N Ganesh, N Guhan, Pawan singh, G.P. Manjunath, S. Datta, Nagasuma R. Chandra and M. Vijayan. Current science. 2004 January 10th , 86 (1).
Crystal structures of Mycobacterium smegmatis RecA and its nucleotide complexes. Datta S, Krishna R, Ganesh N, Chandra NR, Muniyappa K, Vijayan M. J Bacteriol. 2003 Jul;185(14):4280-4.

The effect of stabilizing additives on the structure and hydration of proteins: a study involving tetragonal lysozyme. Datta S, Biswal BK, Vijayan M. Acta Crystallogr D Biol Crystallogr. 2001 Nov ;57(Pt 11):1614-20. Epub 2001 Oct 25.
Crystal structures of Mycobacterium tuberculosis RecA and its complex with ADPAlF(4): implications for decreased ATPase activity and molecular aggregation. Datta S, Prabu MM, Vaze MB, Ganesh N, Chandra NR, Muniyappa K, Vijayan M. Nucleic Acids Res. 2000 Dec 15;28(24):4964-73.

Use of propensities of amino acids to the local structural environments to understand effect of substitution mutations on protein stability. Reddy BV, Datta S, Tiwari S. Protein Eng, 1998 Dec;11(12):1137-45.
Analysis of structural environment of Amino Acids that alter in vitro protein stability. Reddy BVB and Datta S J. Biomol. Str. Dyn. 1997 14: 772.